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Asymptomatic neurosyphilis after doxycycline therapy for early latent syphilis
J M Zenilman1, S Rand, P Barditch
1Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Sexually Transmitted Diseases
|November 1, 1993
Abstract:
A 50-year-old woman allergic to penicillin with early latent syphilis was treated with two courses of doxycycline. Ten months after diagnosis, she had no evidence of serologic response. A lumbar puncture demonstrated asymptomatic neurosyphilis. Penicillin desensitization was performed and she was successfully treated. This case re-emphasizes the need for close serologic follow-up in patients with latent syphilis.