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[Acute kidney failure as a complication of food poisonings]
Abstract:
Literature data and original experience are reviewed on the treatment of alimentary toxoinfections complicated with acute renal failure (ARF). Out of 192 patients prerenal ARF was recorded in 74.5%, renal in 25.5% of the cases. ARF resulted from hemodynamic disturbances, salt and water loss, intoxication. ARF clinical symptoms were poor, the patients developed decompensated metabolic acidosis and hyperazotemia. Pathological and histological evidence is available for 17 patients with "shock kidney". They died of infective toxic shock. The treatment of ARF complicating acute alimentary toxoinfections in 98.9% made a success if implied polyion crystalloid solutions. Hemodialysis was demanded in 1.1% of the cases.
Insights
Acute renal failure (ARF) in alimentary toxoinfections is often prerenal and successfully treated with polyion crystalloid solutions. Only 1.1% of patients required hemodialysis for severe cases.
Area of Science:
- Nephrology
- Infectious Diseases
- Critical Care Medicine
Background:
- Alimentary toxoinfections can lead to acute renal failure (ARF), a serious complication.
- Understanding the types and causes of ARF in this context is crucial for effective management.
Observation:
- A review of 192 patients revealed that 74.5% experienced prerenal ARF and 25.5% had renal ARF.
- Causes included hemodynamic disturbances, dehydration, and intoxication.
- Seventeen patients with "shock kidney" died from infective toxic shock.
Findings:
- ARF presented with subtle clinical symptoms, marked by metabolic acidosis and azotemia.
- Treatment with polyion crystalloid solutions was successful in 98.9% of cases.
- Hemodialysis was necessary for only 1.1% of patients.
Implications:
- Prompt and appropriate fluid resuscitation is key to managing ARF in alimentary toxoinfections.
- Early intervention with crystalloid solutions can prevent progression to severe renal failure and reduce mortality.
- This approach simplifies treatment and minimizes the need for complex interventions like hemodialysis.