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Centrilobular opacities in the lung on high-resolution CT: diagnostic considerations and pathologic correlation
J F Gruden1, W R Webb, M Warnock
1Department of Radiology, San Francisco General Hospital, CA 94110.
AJR. American Journal of Roentgenology
|March 1, 1994
Summary
Understanding secondary lobular anatomy is key for interpreting high-resolution CT lung scans. Centrilobular opacities on CT scans often indicate diseases affecting bronchioles, lymphatics, or pulmonary arteries.
Area of Science:
- Radiology
- Pulmonary Medicine
- Anatomy
Background:
- High-resolution computed tomography (HRCT) is crucial for diagnosing lung diseases.
- Accurate interpretation of HRCT requires detailed knowledge of lung secondary lobular anatomy.
- Centrilobular opacities can signify various pathological processes.
Purpose of the Study:
- To correlate secondary lobular anatomy with high-resolution CT findings.
- To illustrate HRCT manifestations of diseases affecting the centrilobular region.
- To provide pathological correlation for observed CT findings.
Main Methods:
- Review of high-resolution CT scans of the lung.
- Identification of opacities localized to the centrilobular region.
- Correlation with available pathologic data.
Main Results:
- Specific HRCT patterns associated with centrilobular diseases were identified.
- Diseases involving centrilobular bronchioles, lymphatics, and pulmonary arteries were visualized.
- Pathologic correlation confirmed the CT findings in select cases.
Conclusions:
- Knowledge of secondary lobular anatomy enhances HRCT interpretation accuracy.
- Centrilobular opacities on HRCT are indicative of specific disease processes.
- HRCT findings can be reliably correlated with underlying pathology.