Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunologic reactions in chronic wounds

C R Baxter1

  • 1Department of Surgery, University of Texas Southwestern Medical Center, Dallas 75235.

American Journal of Surgery
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute renal failure: the reduction of morbidity and mortality.

Research report. Brooke Army Medical Center. Surgical Research Unit·2014
Same author

Reiter's disease.

British medical journal·2010
Same author

Prophylactic hemodialysis in the treatment of acute renal failure. Annals of Internal Medicine, 53:992-1016, 1960.

Journal of the American Society of Nephrology : JASN·1998
Same author

Skin burn injury and oxidative stress in liver and lung tissues of rabbit models.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies·1995
Same author

Effects of omega-3 and omega-6 fatty acid-rich oils on the cardiovascular system of thermally injured rabbits: changes in plasma triglycerides, plasma cholesterol, relative blood viscosity, platelet count, and bleeding time.

The Journal of burn care & rehabilitation·1995
Same author

Effects of supplemented omega-3 and omega-6 fatty acid rich oils on the cardiovascular system of thermally injured rabbits: changes in plasma and platelet fatty acids.

The Journal of burn care & rehabilitation·1995
Same journal

Innovative management of Anterior Cutaneous Nerve Entrapment Syndrome (ACNES): A meta-analysis and introduction of a new robotic approach with patient-based algorithm.

American journal of surgery·2026
Same journal

Does the risk outweigh the benefit? Clot progression, recanalization & complications of anticoagulation therapy in acute pancreatitis with concomitant splanchnic vein thrombosis.

American journal of surgery·2026
Same journal

High and low body mass index and 90-day postoperative outcomes in patients with Crohn's disease undergoing abdominal surgery.

American journal of surgery·2026
Same journal

Women with firearm injuries: A multicenter mixed-methods study.

American journal of surgery·2026
Same journal

SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

American journal of surgery·2026
Same journal

Using Dr. Google and AI to stay informed.

American journal of surgery·2026
See all related articles

Excessive inflammation can delay wound healing and increase scarring. Occlusive dressings help manage wound environments by preventing tissue death and reducing microbial invasion, thereby limiting inflammation.

Area of Science:

  • Wound healing research
  • Inflammation biology
  • Biomaterials science

Background:

  • Local inflammation initiates wound healing.
  • Prolonged or excessive inflammation can impede healing and worsen scarring.
  • Inflammatory mediators in the wound microenvironment include complement degradation products, leukocyte products, free radicals, enzymes, and microbial components.

Purpose of the Study:

  • To explore the role of inflammation in wound healing.
  • To identify factors that prolong inflammation in wounds.
  • To evaluate the potential of occlusion dressings in managing wound inflammation.

Main Methods:

  • Review of inflammatory cascades in wound healing.
  • Analysis of factors contributing to prolonged inflammation (infection, ischemia, necrotic tissue, foreign bodies).

Related Experiment Videos

  • Discussion of occlusion dressing properties and their impact on wound environment.

    • Main Results:

    • Inflammation is a double-edged sword in wound healing, necessary but potentially detrimental.
    • Wound complications like infection and ischemia exacerbate inflammation.
    • Occlusion dressings can mitigate negative impacts by preventing desiccation and microbial entry.

    Conclusions:

    • Controlling excessive inflammation is crucial for optimal wound healing and scar reduction.
    • Occlusion dressings offer a therapeutic strategy to manage the wound microenvironment.
    • Minimizing necrotic tissue and preventing infection are key to limiting detrimental inflammatory responses.