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[Haptoglobin-Johnson-type and evident ahaptoglobinemia in 2 families]
Abstract:
In two Leipzig families mark carriers of the rare Hp-Johnsontype as well as apparantly genetically associated with this hypohaptoglobinaemias were observed. Demonstration of the Hp-patterns of these mark carriers and comparison with standard Hp-patterns with the help of several methods (starch gel electrophoresis, agar gel diffusion test, immunoelectrophoresis). Short survey of the modern conception for the explanation of the genetic regulation of the Johnson-type.