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MAC reduction of isoflurane by sufentanil

M D Brunner1, P Braithwaite, R Jhaveri

  • 1Department of Anesthesia, Duke University Medical Center, Durham, North Carolina 27710.

British Journal of Anaesthesia
|January 1, 1994
PubMed
Summary

Sufentanil significantly reduces minimum alveolar concentration (MAC) of isoflurane, requiring a plasma concentration of 0.145 ng/mL for 50% reduction. Higher concentrations show a ceiling effect, indicating limited additional potency.

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