[Bone metabolism and Chinese medicinal treatment of menopausal osteoporosis]

48 perimenopausal women were divided into premenopausal (PrM) and postmenopausal (PoM) groups, which were sub-divided into Chinese medicinal herbs (CM) and DES treatment groups, and 12 middle aged women were served as control. E0, E2, T, GH, Ca, P and ALP in the serum and the ratio of Ca/Cr in fasting urine as well as the BMD of right radius was measured. Results showed: The E0, E2 of the PoM were significantly lower than those of the PrM and control groups (P < 0.05, P < 0.01), with no remarkable difference in GH; the T value of PoM was lower than that of control (P < 0.01). Serum Ca and ALP and the ratio of Ca/Cr in fasting urine of the PoM were much higher than those of the control (P < 0.01); the serum Ca and urinary Ca/Cr of the PrM were higher than those of the control (P < 0.05, P < 0.01 respectively). The BMD value of the radius of both PoM and PrM groups were much lower than that of control (P < 0.01), the BMD of the PoM was lower than that of PrM (P < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)