Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clinical-pathological correlation in massive periretinal proliferation

H Laqua, R Machemer

    American Journal of Ophthalmology
    |November 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    An effective sub-quadratic scaling atomic-orbital reformulation of the scaled opposite-spin RI-CC2 ground-state model using Cholesky-decomposed densities and an attenuated Coulomb metric.

    The Journal of chemical physics·2022
    Same author

    First results from the implementation of the ITER diagnostic residual gas analyzer prototype at Wendelstein 7-X.

    The Review of scientific instruments·2019
    Same author

    Generation of organized Lacrimal gland cell spheroids by simulated microgravity.

    Journal of stem cells & regenerative medicine·2014
    Same author

    Amniotic membrane as a matrix for lacrimal gland tissue engineering.

    Journal of stem cells & regenerative medicine·2014
    Same author

    Cultivation of lacrimal gland acinar cells in a microgravity environment.

    The British journal of ophthalmology·2009
    Same author

    Diagnostic developments for quasicontinuous operation of the Wendelstein 7-X stellarator.

    The Review of scientific instruments·2008

    Cellular proliferation in owl monkey eyes with retinal detachment forms membranes, leading to fixed retinal folds. This process, termed massive periretinal proliferation, mimics human conditions like massive vitreous retraction.

    Area of Science:

    • Ophthalmology
    • Cell Biology
    • Veterinary Medicine

    Background:

    • Retinal detachment can trigger cellular proliferation in ocular tissues.
    • Pigment epithelial and glial cells are implicated in post-detachment ocular changes.

    Purpose of the Study:

    • To investigate the cellular proliferation response in owl monkey eyes following retinal detachment.
    • To characterize the formation of membranes and associated retinal folds.

    Main Methods:

    • Histological examination of owl monkey eyes with retinal detachments.
    • Observation of cellular behavior and membrane formation on intraocular structures.

    Main Results:

    • Widespread proliferation of pigment epithelial and glial cells was observed in nearly all detached eyes.

    Related Experiment Videos

  • These cells formed membranes on vitreous structures, inner, and outer retinal surfaces.
  • The extent and location of membranes correlated with the type and severity of fixed retinal folds.

    • Conclusions:

    • Cellular proliferation is a significant response to retinal detachment in owl monkeys.
    • The process can lead to conditions resembling massive vitreous or preretinal retraction in humans.
    • The term massive periretinal proliferation is proposed to describe this ubiquitous cellular response.