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The type III-9 repeat of human fibronectin is encoded by a single exon which is not alternatively spliced
R Gardella1, S Barlati, S Ferraboli
1Department of Biomedical Sciences and Biotechnology, University of Brescia, Italy.
Cell Biology International
|November 1, 1993
Abstract:
Type III homologies of human fibronectin are generally encoded by two exons, with the exception of the ED-A and ED-B repeats which are encoded by a single exon undergoing alternative splicing. We report that also the type III-9 homology is encoded by a single exon. Further more, RT-PCR analysis, performed on mRNA purified from fetal and adult tissues and from normal and tumor-derived cell types, showed that the III-9 region is not undergoing alternative splicing in all samples tested.