Angioleiomyoma involving the sciatic nerve--CT demonstration. Case report
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Updated: Nov 9, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
W W Scott1, R H Hruban, J N Campbell
1Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-8722.
Abstract:
An angioleiomyoma adjacent to the sciatic nerve was responsible for an 11-year history of pain and dysfunction in the sciatic nerve distribution, which required numerous therapeutic procedures and intermittent use of narcotic analgesics. Diagnosis was finally made when results of a sciatic nerve block suggested possible mechanical compression of the nerve and computed tomography examination of the pelvis was extended further caudal than usual, demonstrating the tumor adjacent to the sciatic nerve near the ischial tuberosity. Only one previous case of nerve dysfunction due to impingement by an angioleiomyoma has been reported.
