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Related Experiment Videos

Peripheral intravenous infiltration necrosis

P Yosowitz, D A Ekland, R C Shaw

    Annals of Surgery
    |November 1, 1975
    PubMed
    Summary
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    Extravasation of intravenous calcium salts or 10% dextrose can cause severe tissue damage, especially in infants. Prompt medical intervention is crucial to manage these serious complications and prevent long-term disfigurement.

    Area of Science:

    • Medical Science
    • Pediatric Care
    • Intravenous Therapy

    Background:

    • Intravenous (IV) solutions containing calcium salts and 10% dextrose are commonly used for medical treatment.
    • Peripheral extravasation, the unintended leakage of these solutions into surrounding tissues, can occur during IV administration.

    Observation:

    • Eight patients, including six infants, experienced significant local tissue necrosis due to peripheral extravasation of IV calcium salts and/or 10% dextrose.
    • These incidents led to prolonged hospitalization and, in five cases, severe disfigurement or compromised limb function.

    Findings:

    • The study highlights the severe local tissue damage, including necrosis, resulting from extravasation of specific IV solutions.
    • Treatment involved established surgical procedures such as debridement, early skin grafting, and secondary reconstruction.

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    Implications:

    • Physicians must be aware of the potential for serious sequelae following extravasation of calcium salts and 10% dextrose solutions.
    • Careful administration and monitoring are essential when using these indicated intravenous therapies to mitigate risks.