[Malignant hyperthermia: preoperative prognosis, prevention and treatment]

Malignant hyperthermia, a inheritant metabolic disease can be induced by some anesthetic agents. The morbid conditions and clinical manifestations in two cases of malignant hyperthermia were studied. The two basic conditions are necessary in the occurrence of malignant hyperthermia: familial inheritant defects, i.e. abnormal membranes that encase myosarkoplasm; and contact of anesthetic agents. The main clinical manifestations of malignant hyperthermia include muscular tetanic spasm and abrupt rising of body temperature. Five aspects of early prognosis and prompt treatment are given.