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Updated: Jul 30, 2026

Multifocal Electroretinograms
Published on: December 4, 2011
Visual loss due to progressive multifocal leukoencephalopathy in a heart transplant patient
A R Lewis1, L B Kline, N B Pinkard
1Department of Ophthalmology, University of Alabama at Birmingham.
Abstract:
A 59-year-old male heart transplant recipient experienced progressive visual loss following routine cataract surgery with intraocular lens implantation. Cranial magnetic resonance (MR) imaging suggested and brain biopsy confirmed the cause to be progressive multifocal leukoencephalopathy (PML). The patient died 2 months following cataract surgery. This case illustrates that visual failure may be the initial manifestation of PML, and the ophthalmologist should be aware of this central demyelinating disorder when dealing with immunocompromised patients.
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