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Hepatocellular adenoma: color Doppler US and pathologic correlations
M Golli1, J T Van Nhieu, D Mathieu
1Department of Radiology and Medical Imaging, Hôpital Henri Mondor, Créteil, France.
Radiology
|March 1, 1994
Summary
Color Doppler ultrasound (US) effectively visualizes intratumoral vessels in hepatocellular adenoma (HA). These US findings correlate with pathology, aiding in HA diagnosis and differentiation from other liver lesions.
Area of Science:
- Radiology
- Hepatology
- Vascular Imaging
Background:
- Hepatocellular adenoma (HA) is a benign liver tumor.
- Accurate diagnosis of HA is crucial for patient management.
- Distinguishing HA from other focal liver lesions can be challenging.
Purpose of the Study:
- To characterize the color Doppler ultrasound (US) features of hepatocellular adenoma (HA).
- To correlate US findings with histopathologic data, focusing on vascular structures.
- To assess the utility of color Doppler US in the differential diagnosis of HA.
Main Methods:
- Prospective color Doppler US examination of eleven HA lesions in eight patients.
- Histopathologic confirmation of all studied HA lesions.
- Detailed analysis of intratumoral and peritumoral vascular patterns using Doppler US.
Main Results:
- Central color flow was detected in seven HA lesions.
- Continuous, flat venous spectra (0.20-0.60 kHz) correlated with 1-5 mm intratumoral veins.
- A triphasic venous waveform (1.20 kHz) corresponded to a 10 mm central vein.
- Both venous and arterial peritumoral flow were observed in seven lesions.
Conclusions:
- Color Doppler US reliably detects intratumoral veins in HA.
- The presence of intratumoral and peritumoral vessels visualized by Doppler US correlates with pathologic findings.
- These US characteristics can aid in differentiating HA from focal nodular hyperplasia (FNH).