Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A tissue equivalent phantom for stereotactic radiosurgery localization and dose verification

C W Coffey1, M Sanders, K Cashon

  • 1Neurosurgery Department, University of Kentucky Medical Center, Lexington.

Stereotactic and Functional Neurosurgery
|January 1, 1993
PubMed
Summary

Stereotactic radiosurgery localization and dose verification for the Leksell Gamma Knife were confirmed using a head phantom. A color-doped gel and thermoluminescent dosimetry (TLD) validated dose accuracy within 4% of computer estimates.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum: "AAPM protocol for 40-300 kV x-ray beam dosimetry in radiotherapy and radiobiology".

Medical physics·2023
Same author

Measurement of the pseudoscalar decay constant fDs using charm-tagged events in e+e- collisions at square root s=10.58 GeV.

Physical review letters·2007
Same author

CD4 cell count and initiation of antiretroviral therapy: trends in seven UK centres, 1997-2003.

HIV medicine·2007
Same author

Observation of a Charmed Baryon Decaying to D;{0}p at a Mass Near 2.94 GeV/c;{2}.

Physical review letters·2007
Same author

Observation of decays B0-->Ds(*)+ pi- and B0-->Ds(*)- K+.

Physical review letters·2007
Same author

Isolation facilities for patients with methicillin-resistant Staphylococcus aureus (MRSA): how adequate are they?

The Journal of hospital infection·2007

Area of Science:

  • Neurosurgery
  • Medical Physics
  • Radiation Oncology

Background:

  • Stereotactic radiosurgery requires precise localization and dose verification for effective treatment.
  • The Leksell Gamma Knife is a common tool for radiosurgery, necessitating reliable methods for accuracy assessment.

Purpose of the Study:

  • To evaluate the accuracy of stereotactic localization and dose verification for radiosurgery procedures using the Leksell Gamma Knife.
  • To confirm the precision of imaging techniques (angiography, CT, MR) and dosimetry in a phantom model.

Main Methods:

  • A tissue-equivalent head phantom with a radiation dose-dependent color-doped gel target was used.
  • Stereotactic localization was performed using angiography, CT, or MR, followed by irradiation with the Leksell Gamma Knife.

Related Experiment Videos

  • Thermoluminescent dosimetry (TLD) was employed for experimental dose verification, with results compared to computer-predicted doses.

    • Main Results:

    • The color change in the gel target confirmed accurate stereotactic localization and treatment isocenter.
    • Experimental dose measurements using TLD showed excellent agreement (+/- 4%) with computer dose planning estimates.
    • The study successfully validated the accuracy of the Leksell Gamma Knife's localization and dosimetry capabilities in a phantom setting.

    Conclusions:

    • The utilized phantom model effectively confirmed the stereotactic localization accuracy of the Leksell Gamma Knife.
    • Thermoluminescent dosimetry provides reliable experimental verification of radiation doses delivered by the Gamma Knife.
    • These findings support the safety and efficacy of Leksell Gamma Knife radiosurgery through rigorous phantom-based validation.