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Sweet's syndrome in children

B W Boatman1, R C Taylor, L E Klein

  • 1Department of Pediatrics, University of South Carolina School of Medicine, Columbia.

Southern Medical Journal
|February 1, 1994
PubMed
Summary

Acute febrile neutrophilic dermatosis (Sweet's syndrome) is a rare inflammatory condition. This study presents two pediatric cases, highlighting typical symptoms and prompt response to corticosteroid therapy, despite relapses.

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Area of Science:

  • Dermatology
  • Pediatrics
  • Rheumatology

Background:

  • Acute febrile neutrophilic dermatosis, or Sweet's syndrome, is a rare inflammatory condition.
  • It is characterized by painful, erythematous plaques and a dermal infiltrate of neutrophils.
  • Systemic diseases often accompany Sweet's syndrome, influencing patient prognosis.

Observation:

  • Sweet's syndrome is uncommon in children, with only 17 cases previously reported.
  • This report details two pediatric cases with typical Sweet's syndrome features.
  • Unique presentations included tibial pain in one child and marked leukocytosis in the other.

Findings:

  • Both pediatric patients responded rapidly to systemic corticosteroid treatment.
  • Despite initial therapeutic success, both patients experienced disease relapse.

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  • The findings underscore the importance of thorough medical evaluation in diagnosing Sweet's syndrome.

    • Implications:

    • Early diagnosis and treatment of Sweet's syndrome in children are crucial.
    • Corticosteroid therapy is effective but requires monitoring due to potential relapses.
    • Further research is needed to understand the underlying causes and long-term management of pediatric Sweet's syndrome.