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Sweet's syndrome in children
B W Boatman1, R C Taylor, L E Klein
1Department of Pediatrics, University of South Carolina School of Medicine, Columbia.
Southern Medical Journal
|February 1, 1994
Summary
Acute febrile neutrophilic dermatosis (Sweet's syndrome) is a rare inflammatory condition. This study presents two pediatric cases, highlighting typical symptoms and prompt response to corticosteroid therapy, despite relapses.
Area of Science:
- Dermatology
- Pediatrics
- Rheumatology
Background:
- Acute febrile neutrophilic dermatosis, or Sweet's syndrome, is a rare inflammatory condition.
- It is characterized by painful, erythematous plaques and a dermal infiltrate of neutrophils.
- Systemic diseases often accompany Sweet's syndrome, influencing patient prognosis.
Observation:
- Sweet's syndrome is uncommon in children, with only 17 cases previously reported.
- This report details two pediatric cases with typical Sweet's syndrome features.
- Unique presentations included tibial pain in one child and marked leukocytosis in the other.
Findings:
- Both pediatric patients responded rapidly to systemic corticosteroid treatment.
- Despite initial therapeutic success, both patients experienced disease relapse.
- The findings underscore the importance of thorough medical evaluation in diagnosing Sweet's syndrome.
Implications:
- Early diagnosis and treatment of Sweet's syndrome in children are crucial.
- Corticosteroid therapy is effective but requires monitoring due to potential relapses.
- Further research is needed to understand the underlying causes and long-term management of pediatric Sweet's syndrome.