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Related Experiment Videos

Pretransplant urologic evaluation

C C Yang1, M C Rohr, D G Assimos

  • 1Department of Urology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina.

Urology
|February 1, 1994
PubMed
Summary
This summary is machine-generated.

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A standardized urologic protocol for transplant candidates identified malignancies, including renal cell carcinoma. Renal ultrasonography is recommended for all, while voiding cystourethrography and endoscopic evaluation have specific indications.

Area of Science:

  • Urology
  • Transplant Medicine
  • Diagnostic Imaging

Background:

  • Pretransplant urologic evaluations are recommended but lack validated efficacy.
  • Standardized protocols are needed for adult transplant candidates.

Purpose of the Study:

  • To evaluate a standardized urologic diagnostic protocol for adult transplant candidates.
  • To determine the efficacy of specific urologic evaluations in this population.

Main Methods:

  • Prospective evaluation of 100 adult transplant candidates.
  • Utilized history, physical exam, renal ultrasonography (US), voiding cystourethrography (VCUG), urinalysis, and urine culture.
  • Performed cystoscopy and retrograde pyelography as indicated.

Main Results:

Related Experiment Videos

  • Urologic malignancies diagnosed in 3 patients (prostate, bladder, renal cell carcinoma).
  • Renal US detected renal cell carcinoma in 1 patient; overall low yield.
  • VCUG abnormalities found in 26 patients; normal in non-diabetics without symptoms/history of UTI.
  • Endoscopic evaluation for hematuria identified a bladder tumor in 1 of 13 patients.
  • Endoscopic evaluation for sterile pyuria revealed no significant abnormalities.

Conclusions:

  • Renal US is recommended for all adult transplant candidates due to renal cell carcinoma prevalence.
  • VCUG is recommended, but may be omitted in non-diabetics without voiding symptoms or UTI history.
  • Endoscopic evaluation is warranted for hematuria, but potentially not for sterile pyuria.