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[Pregnancy after kidney transplantation]
C Aichberger1, W Lechner, D Ofner
1Abteilung für Transplantationschirurgie, I. Universitätsklinik für Chirurgie, Innsbruck.
Wiener Klinische Wochenschrift
|January 1, 1993
Summary
Women with stable kidney transplants can safely become pregnant, with risks to both mother and child appearing low. Specialized care centers are recommended for managing these complex pregnancies.
Area of Science:
- Nephrology
- Reproductive Medicine
- Transplantation Immunology
Context:
- Pregnancy in renal allograft recipients presents unique challenges.
- Assessing the impact of pregnancy on graft function and fetal outcomes is crucial.
- Previous studies on pregnancy post-kidney transplantation have yielded varied results.
Purpose:
- To evaluate the outcomes of pregnancy in women with kidney allografts.
- To determine the safety and risks associated with conception and gestation after renal transplantation.
- To assess the long-term effects on graft function and infant health.
Summary:
- Eleven women experienced 13 live births after a mean of 39.6 months post-transplantation.
- Graft function remained stable in most recipients, but two cases showed deterioration leading to graft loss.
- All deliveries were via caesarean section; premature birth and infant mortality occurred in a complicated twin pregnancy.
Impact:
- Pregnancy is feasible and generally safe for women with stable renal allograft function.
- Close monitoring and specialized care are essential for successful outcomes.
- Findings support allowing pregnancy in carefully selected renal transplant recipients.