Evidence for noninvolvement of brain glycoprotein metabolism in escape training

In two experiments, 21-day-old Sprague-Dawley rats received escape training in a two-choice four-alley water maze. Following training, glycosyl transferase activities of brain microsomal fractions were assayed in control and experimental animals. No significant group differences were observed in the extent of transfer of galactose and N-acetylgalactosamine to endogenous or exogenous acceptors. The results suggested a lack of participation of whole brain glycoprotein metabolism in an escape learning situation.