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Radial keratotomy does not affect intraocular pressure

S M Sastry1, R D Sperduto, G O Waring

  • 1National Eye Institute, Biometry and Epidemiology Program, National Institutes of Health, Bethesda, MD 20892.

Refractive & Corneal Surgery
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

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Radial keratotomy surgery did not significantly reduce intraocular pressure (IOP) in patients within one year. This finding held true even for individuals with higher baseline IOP, suggesting no IOP-lowering effect from this procedure.

Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Ocular Physiology

Background:

  • Emerging evidence suggested radial keratotomy might lower intraocular pressure (IOP).
  • This potential secondary effect warranted further investigation.

Purpose of the Study:

  • To investigate the relationship between radial keratotomy and intraocular pressure (IOP).
  • To determine if radial keratotomy influences IOP levels in the year following surgery.

Main Methods:

  • Comparison of mean IOP between operated and non-operated eyes over one year in the PERK study.
  • Analysis included a subset of patients with baseline IOP of 15 mm Hg or greater.

Main Results:

  • No statistically significant difference in mean IOP between operated and non-operated eyes was observed (p = .18).

Related Experiment Videos

  • IOP changes over time were not clinically different between surgical and non-surgical eyes.
  • Results remained consistent when analyzing eyes with higher baseline IOP.

    • Conclusions:

    • Radial keratotomy performed in the PERK study demonstrated no effect on IOP within one year post-surgery.
    • The findings do not support radial keratotomy as a method for reducing intraocular pressure.