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Effect of neonatal gonadectomy on lymphocytes population and blast formation in aged rats
I Ikarashi1, K Tauchi, M Yukawa
1Imamichi Institute for Animal Reproduction, Niihari, Japan.
The Journal of Veterinary Medical Science
|December 1, 1993
Abstract:
In male rats gonadectomized at birth, the blast formation reaction of lymphocytes was significantly lower at 114 weeks of age, than that of non-gonadectomized controls, whereas the lymphocyte subpopulation was similar. The thymus of neonatally castrated rats of age 114 weeks was histologically normal, decreasing in weight of 68% of that of non-castrated rats.