[The clonogenic properties of the bone marrow in dogs during distraction osteogenesis]

The status of canine hemopoietic and stromal progenitor cells in regeneration of bone tissue was studied in distraction osteosynthesis, by using the bone marrow culture technique in the diffusion chambers. Normal osteogenesis was demonstrated to be characterized by certain phase changes in the cloning of progenitor cells of myelopoiesis, whereas abnormal osteogenesis, the activity of hemopoietic cells remained virtually unchanged, but the cloning of CFU-F increased in intact bones.