Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serum ferritin in thyroid cancer

U R Deshpande1, G D Nadkarni, A M Samuel

  • 1Radiation Medicine Centre, Bhabha Atomic Research Centre, Bombay, India.

Thyroid : Official Journal of the American Thyroid Association
|January 1, 1993
PubMed
Summary

Serum ferritin levels in thyroid cancer patients may indicate metastasis and histological type, though not a direct tumor marker. Higher levels were seen in metastatic and follicular carcinoma cases compared to controls.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Missing data may lead to changes in hip fracture database studies: a study of the American College of Surgeons National Surgical Quality Improvement Program.

The bone & joint journal·2018
Same author

Surgery for a fracture of the hip within 24 hours of admission is independently associated with reduced short-term post-operative complications.

The bone & joint journal·2017
Same author

Do we really know our patient population in database research? A comparison of the femoral shaft fracture patient populations in three commonly used national databases.

The bone & joint journal·2016
Same author

General versus spinal anaesthesia for patients aged 70 years and older with a fracture of the hip.

The bone & joint journal·2015
Same author

Mycobacterium tuberculosis 38kDa antigen and its encoding gene-experience in diagnostic applications.

Indian journal of clinical biochemistry : IJCB·2012
Same author

Guidelines in the management of thyroid cancer.

The Journal of the Association of Physicians of India·2011

Area of Science:

  • Endocrinology
  • Oncology
  • Biochemistry

Background:

  • Serum ferritin is a nonspecific tumor marker.
  • Thyroid cancer patients studied were hypothyroid post-thyroidectomy.
  • Previous research on serum ferritin in thyroid cancer is limited.

Purpose of the Study:

  • To investigate serum ferritin levels in thyroid cancer patients.
  • To assess the correlation between serum ferritin and metastasis.
  • To evaluate the relationship between serum ferritin and histological type of thyroid cancer.

Main Methods:

  • Studied 102 thyroid cancer patients off thyroxine for 1 month.
  • Measured serum ferritin levels.
  • Compared levels between thyroid cancer patients, controls, and primary hypothyroid patients.
  • Analyzed differences based on metastasis and histological type (follicular vs. papillary carcinoma).

Main Results:

  • Serum ferritin levels were not significantly different in thyroid cancer patients compared to controls.
  • Thyroid cancer patients showed higher serum ferritin than primary hypothyroid patients.
  • Significantly higher serum ferritin levels were observed in patients with metastasis compared to those without.
  • Follicular carcinoma patients exhibited higher ferritin levels than papillary carcinoma patients.

Conclusions:

  • Serum ferritin may not be a reliable tumor marker for thyroid cancer.
  • Serum ferritin levels appear sensitive to the presence of metastasis in thyroid cancer.
  • Serum ferritin levels may aid in distinguishing histological types of thyroid cancer, particularly follicular vs. papillary.

Related Experiment Videos