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Low-dose aspirin in pregnancy: changes in patterns of prescription in The Netherlands
1Institute of Obstetrics and Gynecology, Erasmus University School of Medicine and Health Sciences, Rotterdam, The Netherlands.
Objective:
To describe patterns of prescription in the Netherlands of low-dose aspirin in pregnancy.
Design:
Anonymous written inquiry in 1989 and 1991.
Subjects:
Gynecologists in the Netherlands (619 in 1989 and 618 in 1991), practicing in training and non-training hospitals.
Main Outcome Measures:
Prescription rates for prevention of pregnancy-induced hypertension and fetal growth retardation, or for intention to treat.
Results:
The response rates were 52% in 1989 and 58% in 1991, covering approximately 61% and 62%, respectively, of the practicing gynecologists in the Netherlands. The use for prevention increased from 53% to 79% and for therapeutic intentions from 25% to 48%.
Conclusion:
The prescription rate for low-dose aspirin increased markedly from 1989 to 1991, without evidence for its benefit from the literature published in the same time period.