Jove
Visualize
Contact Us

Related Experiment Videos

[Pulmonary hypertension and systemic sclerosis]

S Morelli1, P De Marzio, G Valesini

  • 1Istituto di I Clinica Medica, Università di Roma La Sapienza.

Giornale Italiano Di Cardiologia
|September 1, 1993
PubMed
Summary

Pulmonary hypertension frequently affects systemic sclerosis (SS) patients, impacting prognosis. Doppler echocardiography effectively detects this complication early in both limited and diffuse SS forms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Activity standardization and determination of nuclear decay data of <sup>212</sup>Pb at LNE-LNHB and first measurements in the SIR at BIPM.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

First report of fatal autochthonous angiostrongylosis in a dog in Greece.

Veterinary parasitology, regional studies and reports·2021
Same author

Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus.

Scientific reports·2020
Same author

Real-world efficacy and safety of lenvatinib: data from a compassionate use in the treatment of radioactive iodine-refractory differentiated thyroid cancer patients in Italy.

European journal of cancer (Oxford, England : 1990)·2019
Same author

Anti-D4GDI antibodies activate platelets in vitro: a possible link with thrombocytopenia in primary antiphospholipid syndrome.

Arthritis research & therapy·2019
Same author

CD44v3 and CD44v6 isoforms on T cells are able to discriminate different disease activity degrees and phenotypes in systemic lupus erythematosus patients.

Lupus·2019
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Cardiology
  • Rheumatology
  • Pulmonology

Background:

  • Pulmonary involvement is a common and serious complication of systemic sclerosis (SS).
  • Pulmonary hypertension (PH) in SS often goes unrecognized until advanced stages.
  • Early detection of PH is crucial for managing SS patients.

Purpose of the Study:

  • To assess the prevalence of pulmonary hypertension in patients with systemic sclerosis (SS).
  • To evaluate the utility of Doppler echocardiography for noninvasive detection of PH in SS.

Main Methods:

  • Doppler echocardiography was used to noninvasively measure pulmonary artery systolic pressure.
  • 31 patients diagnosed with systemic sclerosis were included in the study.

Main Results:

  • Pulmonary hypertension was detected in 48.4% of SS patients.
  • The prevalence of PH was similar in both limited and diffuse SS subtypes.
  • PH was generally mild, with only two cases showing significantly elevated pressures.

Conclusions:

  • Pulmonary hypertension is a frequent complication in systemic sclerosis, affecting limited and diffuse forms equally.
  • Doppler echocardiography is a valuable, noninvasive tool for early PH detection in SS patients.
  • Early identification of PH allows for timely therapeutic interventions to prevent disease progression.

Related Experiment Videos