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Related Experiment Video

Updated: May 11, 2026

Murine Model of Allergen Induced Asthma

Murine Model of Allergen Induced Asthma

Published on: May 14, 2012

Asthma caused by live fish bait

A Siracusa¹, P Bettini, R Bacoccoli

¹Institute of Occupational Medicine, University of Perugia, Italy.

The Journal of Allergy and Clinical Immunology

|February 1, 1994

Summary

This summary is machine-generated.

Live fish bait (LFB) can cause allergic reactions like asthma and rhinoconjunctivitis. Exposure to LFB emanations is a common sensitizing agent for IgE-mediated asthma.

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Area of Science:

Allergy and Immunology
Occupational Health
Environmental Health

Background:

Live fish bait (LFB) is widely used by anglers.
Reported cases of asthma, rhinoconjunctivitis, and urticaria linked to LFB exposure exist.

Purpose of the Study:

To investigate respiratory symptoms in individuals exposed to LFB.
To identify allergens and assess the impact of LFB on respiratory function.

Main Methods:

Studied 14 subjects with LFB-associated respiratory symptoms.
Performed skin prick tests and RASTs with insect and worm extracts.
Monitored lung function and bronchial responsiveness before and after LFB exposure.

Main Results:

13 subjects had asthma, 14 had rhinoconjunctivitis, and 3 had urticaria.
Positive skin tests or RASTs were observed for Lucilia caesar, Galleria mellonella, and Tenebrio molitor extracts.
Late asthmatic responses occurred in 3 subjects, linked to increased bronchial responsiveness.

Conclusions:

LFB emanations are potent sensitizers capable of causing IgE-mediated asthma.
Occupational and recreational exposure to LFB is common.
LFB should be recognized as a potential sensitizing agent for asthma.