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[Successful surgery for pulmonary aspergillosis progressing to subacute process]
H Wakayama1, Y Itoh, M Noguchi
1Department of Respiratory Diseases, Nagoya Daini Red Cross Hospital, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi
|December 1, 1993
Summary
This case study highlights a rare bronchial aspergilloma in a patient with rheumatoid lung disease. Surgical resection proved effective for this severe pulmonary fungal infection.
Area of Science:
- Pulmonology
- Mycology
- Infectious Diseases
Background:
- A 59-year-old woman with diabetes and rheumatoid arthritis received prednisolone for rheumatoid lung disease.
- She presented with fever and bloody sputum, indicative of a significant pulmonary issue.
Observation:
- Imaging revealed a massive shadow in the right lower lung, later identified as a giant mass with unclear margins on CT scan.
- Bronchial brushing confirmed Aspergillus hyphae, leading to a diagnosis of pulmonary aspergillosis.
Findings:
- Standard antifungal treatment yielded unsatisfactory results.
- Surgical resection was performed, revealing a bronchial aspergilloma within an enlarged bronchus, surrounded by inflammatory cells.
Implications:
- This case demonstrates a subacute progression of pulmonary aspergillosis, influenced by the patient's immune response.
- Surgical resection is recommended for localized pulmonary aspergillosis, offering a potentially curative treatment option.