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Updated: Aug 3, 2026

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
Published on: June 7, 2015
[Studies of releasing rate of pilocarpine hydrochloride from hydrogel eye ointments]
T Kecik1, J Szlaski, L Portacha
1Katerdy i Kliniki Chorób Oczu AM, Warszawie.
Abstract:
The aim of the study was to evaluate the usefulness of hydrophilic base with pilocarpine hydrochloride. Comparisons were made between releasing rate of pilocarpine hydrochloride from hydrophilic and lipophilic bases into water and artificial tears. It was found that pilocarpine hydrochloride was released in the amount 30-40 times greater from hydrogel bases compared to lipophilic. The releasing rate of drugs from hydrogel ointments increases with the increased colloid concentration and with decreased of drug concentration in the base.
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