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Published on: March 18, 2020
Early glottic carcinoma treated with open laryngeal procedures
J V Thomas1, K D Olsen, H B Neel
1Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minn.
Archives of Otolaryngology--Head & Neck Surgery
|March 1, 1994
Summary
Open laryngeal procedures show excellent long-term survival and low recurrence rates for early glottic carcinoma. These versatile surgical options effectively manage T1 glottic cancers.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Oncology
Background:
- Open laryngeal procedures have been utilized for decades in managing laryngeal cancers.
- Assessing the long-term outcomes of these procedures is crucial for treatment planning.
Purpose of the Study:
- To determine the recurrence rates and long-term survival of patients treated with open laryngeal procedures for early glottic carcinoma.
Main Methods:
- Retrospective analysis of 159 patients with early glottic carcinoma treated between 1976 and 1986.
- Surgical interventions included frontolateral partial vertical laryngectomies, laryngofissures with cordectomy, hemilaryngectomies, and anterior commissure procedures.
- Kaplan-Meier method was used to estimate survival and recurrence probabilities.
Main Results:
- The 3- and 5-year survival probabilities were 91% and 84%, respectively.
- The 3- and 5-year local recurrence-free probabilities were 94% and 93%, respectively.
- Eleven patients experienced recurrence, with 3 of 11 salvaged after re-treatment.
Conclusions:
- Open laryngeal procedures are effective and versatile treatments for select cases of early glottic carcinoma.
- These procedures demonstrate excellent long-term survival and local control rates.

