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CT-pathologic correlation in nodular bronchioloalveolar carcinoma
Journal of Computer Assisted Tomography
|March 1, 1994
Summary
Computed tomography (CT) findings like the CT halo sign can suggest nodular bronchioloalveolar carcinoma (BAC). However, definitive diagnosis of BAC requires histologic examination.
Area of Science:
- Pulmonary Medicine
- Radiology
- Oncology
Background:
- Nodular bronchioloalveolar carcinoma (BAC) is a subtype of lung cancer.
- Accurate preoperative diagnosis is crucial for effective treatment planning.
Purpose of the Study:
- To correlate the histopathologic features of resected nodular BAC with their appearance on thin-section CT.
- To identify specific CT findings indicative of nodular BAC.
Main Methods:
- Retrospective review of thin-section CT scans and pathologic examinations from 11 patients with resected nodular BAC.
- Analysis of nodule size, tumor-lung interface, and internal characteristics on CT.
- Correlation of CT findings with histopathologic results.
Main Results:
- CT showed spiculated, lobulated, or irregular borders in 82% of nodules.
- The CT halo sign was observed in 18% of cases, correlating with air-containing glandular spaces.
- Internal serpentine radiolucencies were also noted, linked to tumor histology.
Conclusions:
- The CT halo sign and serpentine radiolucencies are valuable additions to the CT findings for nodular BAC.
- Histologic examination remains essential for confirming the diagnosis of BAC.