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[Infection in patient with malignant disease]
1First Department of Surgery, Nagoya City University Medical School.
Nihon Rinsho. Japanese Journal of Clinical Medicine
|February 1, 1994
Summary
Patients with malignant disease face higher infection rates compared to those with benign conditions. Key bacteria identified include Enterococcus and Staphylococcus in malignant cases, and E. coli in benign cases, informing targeted prevention strategies.
Area of Science:
- Infectious Diseases
- Oncology
- Microbiology
Context:
- Patients with malignant disease exhibit a higher susceptibility to infections.
- Biliary tract malignancies are associated with increased postoperative infection risks.
- Intraoperative contamination poses a significant threat in patients with malignant conditions.
Purpose:
- To compare infection rates between patients with malignant and benign diseases.
- To identify predominant bacterial pathogens in infections associated with malignant and benign diseases.
- To evaluate the significance of bacterial isolation from intraoperative bile and wound cultures in malignant disease patients.
Summary:
- Infection rates were significantly higher in patients with malignant disease versus benign disease.
- Enterococcus spp. and Staphylococcus spp. were predominant in malignant disease infections, while E. coli dominated in benign disease infections.
- Bacterial isolation rates from intraoperative bile and wound swabs were higher in malignant disease patients, indicating increased contamination risk.
Impact:
- Highlights the critical need for enhanced infection control measures in patients with malignant disease.
- Suggests prophylactic antibiotic therapy targeting specific bacteria isolated from bile is crucial for preventing postoperative infections.
- Provides essential etiological data for developing targeted antimicrobial strategies in oncology patients.