The enhancing effect of multiple sclerosis brain homogenates on the active E rosette forming lymphocytes

Lymphocytes from 15 of 17 patients with clinically well defined multiple sclerosis (MS) responded to all four MS brain homogenates as assayed by active E rosette test. Lymphocytes from only one neurological patient, out of 18 tested, responded to MS brain homogenates. The nature of the stimulating agent from MS brains remains to be determined.