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[Hirsutism]

V Allali-Zerah1, J Mahoudeau

  • 1Service d'endocrinologie, CHU, Caen.

La Revue Du Praticien
|November 15, 1993
PubMed
Summary

Hirsutism, a condition of male-pattern hair growth in women, is diagnosed using plasma testosterone levels. Treatment involves addressing the cause and symptomatic relief with antiandrogens and oestrogens.

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Area of Science:

  • Endocrinology
  • Dermatology

Context:

  • Hirsutism presents as male-pattern hair distribution in women.
  • Causes include adrenal or ovarian hypersecretion of androgens or increased cutaneous 5 alpha-reductase activity.
  • Diagnosis relies on physical examination and plasma testosterone levels.

Purpose:

  • To outline the diagnostic approach to hirsutism based on plasma testosterone levels.
  • To detail the differential diagnoses for hirsutism.
  • To describe current treatment strategies for hirsutism.

Summary:

  • Plasma testosterone levels guide hirsutism diagnosis: >1.2 ng/mL suggests tumors or congenital adrenal hyperplasia; <0.6 ng/mL indicates idiopathic hirsutism.
  • Intermediate testosterone levels necessitate investigation for polycystic ovarian disease, adrenal hyperplasia, or tumors.
  • Treatment is etiological when possible, but symptomatic management with antiandrogens and oestrogens is standard, alongside depilation.

Impact:

  • Accurate diagnosis based on testosterone levels is crucial for targeted hirsutism management.
  • Effective symptomatic treatment has significantly improved outcomes for women with hirsutism.
  • Understanding androgen pathways and treatment options transforms hirsutism care.

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