[Histologic changes in lungs of mice experimentally infected with amoebae of the "limax" group]

The studies revealed that the infection with the "limax" group amoebae resulted in the severe changes in the respiratory system: in interstitial pneumonia, the injuries of the bronchi, the bronchioles and the blood vessels. The histopathological examinations showed the focal destruction of the alveoli in case of the mild amoeba invasion while the massive invasion caused the complete destruction of the respiratory epithelium, the blood vessels, the bronchi and the bronchioles. Apart from all the changes in the alveoli, in most cases the significant pulmonary hyperaemia and the numerous blood foci were observed. Moreover, the histopathological changes in the blood vessels, the bronchi and the bronchioles consisting in the epithelial destruction and the laceration of the blood vessel walls and the bronchioles were disclosed.