Genetic serum protein markers in eight south Indian caste and tribal populations

A total of n = 769 unrelated male and female individuals from eight endogamous caste (Brahmin, Kapu, Yadava, Relli) and tribal (Bagatha, Kotia, Manne Dora, Konda Dora) populations living in various districts of Andhra Pradesh (India) have been typed for haptoglobin (HP) types and transferrin (TF), group specific component (GC) and alpha 1-antitrypsin (PI) subtypes. The genetic heterogeneity among these population groups is considerable. This can be explained by lacking or at least only minimal gene flow among these caste and tribal groups, by which differences in their genetic profiles caused by locally acting genetic differentiation factors such as drift could be preserved.