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Updated: Sep 26, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Urinary tract infection during pregnancy: its association with maternal morbidity and perinatal outcome
L A Schieve1, A Handler, R Hershow
1School of Public Health, University of Illinois at Chicago 60680.
Objectives:
The effects of antepartum urinary tract infection on adverse maternal and perinatal outcomes were examined. Antepartum urinary tract infection has been previously implicated as a risk factor for numerous outcomes.
Methods:
Crude and multivariable analyses were performed with a perinatal registry cohort of 25,746 mother/infant pairs.
Results:
Elevated risks were observed for exposure to urinary tract infection and low birthweight, prematurity, preterm low birthweight, premature labor, hypertension/preeclampsia, maternal anemia, and amnionitis. Urinary tract infection was associated with perinatal death only among subjects 20 to 29 years of age.
Conclusions:
These findings underscore the importance of antepartum urine screening to identify patients at risk for adverse outcomes.
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