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Correlation of asymmetry of visual field loss with optic disc topography in normal-tension glaucoma
Objective:
To compare the differences in optic disc configuration with different stages of visual field loss in normal-tension glaucoma.
Design:
Interocular pairwise comparisons.
Setting:
Glaucoma clinic of a teaching hospital.
Patients:
Thirteen patients with normal-tension glaucoma and asymmetric visual field loss of at least 2.5 dB in the mean defect of the visual field indexes.
Interventions:
Areas under the optic disc profiles mapped from values for radial sections of the optic disc measured at intervals of 30 degrees and expressed as percentages of the area of a rectangle were obtained from stereophotographs with a computerized image analysis system. Visual fields were tested with automated perimetry (OCTOPUS), using program G1.
Main Outcome Measure:
Correlation analyses between the interocular differences in the areas under the optic disc profile and the interocular differences in the visual field indexes.
Results:
The correlation coefficients between the interocular differences in mean defect and those of the area under the optic disc profile in the superior to temporal sections ranged from -.71 to -.61 (.007 < P < .028). The interocular differences in loss variance correlated with the differences in the area under the optic disc profile in the superior section (r = -.61, P = .0252).
Conclusion:
The differences in visual field loss between the two eyes in normal-tension glaucoma appear mainly to reflect morphometric changes in the superior half of the optic disc.