Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The peritoneal equilibration test in children

J D Hanna1, J W Foreman, T W Gehr

  • 1Department of Pediatrics, Children's Medical Center, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0498.

Pediatric Nephrology (Berlin, Germany)
|December 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A low socio-economic status is an additional risk factor for glucose intolerance in high risk Hong Kong Chinese.

European journal of epidemiology·2001
Same author

Change of glycaemic status in Chinese subjects with impaired fasting glycaemia.

Diabetic medicine : a journal of the British Diabetic Association·2001
Same author

Important role of cardiac spect imaging in patients undergoing percutaneous transluminal coronary angioplasty.

Chinese medical journal·2001
Same author

Diabetes mellitus--a special medical challenge from a Chinese perspective.

Diabetes research and clinical practice·2001
Same author

Obesity, insulin resistance and isolated low high-density-lipoprotein cholesterol in Chinese subjects.

Diabetic medicine : a journal of the British Diabetic Association·2001
Same author

Consultation with the specialist: renal tubular acidosis.

Pediatrics in review·2001

Children and adults show similar glucose absorption during peritoneal dialysis, but children have different creatinine clearance and drain volumes when adjusted for body surface area versus body weight. This highlights age-related differences in peritoneal dialysis efficiency.

Area of Science:

  • Nephrology
  • Pediatric Nephrology
  • Renal Replacement Therapy

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) and continuous cycling peritoneal dialysis are common renal replacement therapies.
  • Understanding age-specific differences in peritoneal dialysis (PD) is crucial for optimizing treatment protocols.

Purpose of the Study:

  • To compare the peritoneal equilibration test (PET) parameters between pediatric and adult patients undergoing CAPD/continuous cycling peritoneal dialysis.
  • To investigate age-related variations in peritoneal transport and fluid dynamics.

Main Methods:

  • A standardized peritoneal equilibration test (PET) protocol was applied to 8 children and 9 adults on CAPD/continuous cycling peritoneal dialysis.
  • Key parameters assessed included glucose and creatinine transport, dialysate/plasma (D/P) ratios, drain volume, and ultrafiltration.

Related Experiment Videos

Main Results:

  • Children exhibited faster glucose equilibration but similar glucose absorption percentages compared to adults.
  • Peritoneal creatinine clearance and drain volume, when scaled to body surface area, were lower in children but normalized when adjusted for body weight.
  • Children had higher initial D/P creatinine ratios, which converged with adult values over time.

Conclusions:

  • While glucose absorption is comparable, age influences peritoneal creatinine transport and fluid removal dynamics when normalized to body surface area.
  • Weight normalization reveals similar peritoneal transport characteristics between children and adults, suggesting body composition is a key factor.
  • These findings underscore the importance of individualized PD prescription based on patient-specific factors like age and body weight.