Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Partial replacement of the heart]

W Fasching, M Deutsch, W Haider

    Langenbecks Archiv Fur Chirurgie
    |January 1, 1975
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pharmacologically Induced Heart Failure for the Evaluation of Circulatory Assistance.

    Artificial organs·2017
    Same author

    Interventional treatment methods in patients with Marfan Syndrome.

    Images in paediatric cardiology·2012
    Same author

    Results of open heart surgery in Jehovah's Witnesses patients.

    The Journal of cardiovascular surgery·2009
    Same author

    Bail-out visceral bypass grafting for acute intestinal ischemia after endovascular stent-graft placement in a complicated type B dissection.

    The Thoracic and cardiovascular surgeon·2009
    Same author

    Secretion of soluble ST2 - possible explanation for systemic immunosuppression after heart surgery.

    The Thoracic and cardiovascular surgeon·2009
    Same author

    Development of proteinuria after switch to sirolimus-based immunosuppression in long-term cardiac transplant patients.

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2008
    Same journal

    [Popliteal artery entrapment syndrome. Case report of an 11-year-old boy].

    Langenbecks Archiv fur Chirurgie·1997
    Same journal

    [Local effects and changes in wound drainage in the free peritoneal cavity].

    Langenbecks Archiv fur Chirurgie·1997
    Same journal

    [Gasless video-endoscopic implantation of aortobifemoral vascular prostheses via extraperitoneal approach in the animal experiment].

    Langenbecks Archiv fur Chirurgie·1997
    Same journal

    [Procalcitonin. A new marker for acute phase reaction in acute pancreatitis].

    Langenbecks Archiv fur Chirurgie·1997
    Same journal

    [Myocutaneous flap as reliable defect coverage in high grade pelvic decubitus ulcers. Classification, therapeutic concept and presentation of personal patient sample of 16 years].

    Langenbecks Archiv fur Chirurgie·1997
    Same journal

    [Merkel cell tumor or neuroendocrine skin carcinoma].

    Langenbecks Archiv fur Chirurgie·1997
    See all related articles

    A novel ventricular-aortic blood pump successfully replaced the left heart function in calves, significantly reducing myocardial oxygen consumption. Long-term studies show the body fully adapts to this artificial organ for up to 73 days.

    Area of Science:

    • Biomedical Engineering
    • Cardiovascular Physiology
    • Medical Devices

    Context:

    • Heart failure presents a significant clinical challenge.
    • Current treatments have limitations.
    • Advanced artificial organs are needed for cardiac support.

    Purpose:

    • To develop and evaluate a ventricular-aortic blood pump for functional left heart replacement.
    • To assess the hemodynamic performance and physiological impact of the device.

    Summary:

    • A ventricular-aortic blood pump was engineered for functional left heart replacement.
    • Hemodynamic experiments demonstrated the pump's capacity to handle total cardiac output in calves (<85 kg).
    • Significant reduction in myocardial oxygen consumption (40%) was observed, alongside complete physiological adaptation up to 73 days in long-term studies.

    Related Experiment Videos

    Impact:

    • This artificial organ shows promise for treating severe heart failure.
    • Potential to improve patient outcomes and quality of life.
    • Highlights advancements in mechanical circulatory support systems.