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A subpopulation of olivocerebellar projection neurons express neuropeptide Y
T Ueyama1, T Houtani, H Nakagawa
1Department of Anatomy, Kansai Medical University, Osaka, Japan.
Brain Research
|January 21, 1994
Abstract:
By neuropeptide Y (NPY) immunohistochemistry and in situ hybridization histochemistry with digoxigenin-labeled oligonucleotide probes for this peptide, a subpopulation of neurons in the caudal portions of the rat dorsal and medial accessory olives were found to express NPY immunoreactivity and mRNA. In the cerebellum, NPY-immunolabeled climbing fibers were distributed to the flocculus and parts of vermal cortex. The results suggest particular association of NPY with the climbing fiber system presumably mediating spinal, visual and vestibular inputs.