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Pulmonary sequestration with primary blastomycosis. Failure of ketoconazole therapy after resection
R A Serneels1, G S Marshall, J Wampler
1Department of Pediatrics, University of Louisville School of Medicine, Ky.
Chest
|April 1, 1993
Abstract:
Infection with Blastomyces dermatitidis developed in a girl with occult pulmonary sequestration. Six months after resection, while receiving ketoconazole, she developed an abscess due to B dermatitidis over the scar from thoracotomy, with a sinus tract to the eighth rib. This was successfully managed with débridement, rib resection, and amphotericin B. Contiguous bone involvement should be suspected in sequestra infected with this organism; débridement and therapy with amphotericin B might be indicated.