Age-related changes in the human lens: a comparison of Scheimpflug photography and lens density index

Two quantitative techniques, Scheimpflug photography and the lens density index (LDI), were used to measure lens density in 52 patients. In the Scheimpflug technique, a digitized slitlamp camera provides peak and average nuclear density based on a densitometric analysis of the lens nucleus. The LDI is a psychophysical measurement of the difference between retinal scotopic thresholds for two wave-lengths of light. Both the Scheimpflug technique and LDI revealed an age-related increase in lens density. Peak and average nuclear density were highly correlated with the LDI.