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Gadolinium-enhanced MR aortography

M R Prince1

  • 1Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston.

Radiology
|April 1, 1994
PubMed
Summary
This summary is machine-generated.

Intravenous infusion of paramagnetic contrast material during magnetic resonance (MR) aortography enables preferential arterial enhancement. This technique accurately detects aorta and iliac artery diseases, including stenosis, occlusion, and aneurysms.

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Area of Science:

  • Radiology
  • Medical Imaging

Background:

  • Magnetic resonance (MR) aortography is crucial for diagnosing aortic diseases.
  • Achieving optimal arterial enhancement without venous overlap is a challenge.

Purpose of the Study:

  • To assess the efficacy of continuous intravenous paramagnetic contrast material infusion for preferential arterial enhancement in MR aortography.

Main Methods:

  • 125 patients with suspected aorta or aortic branch vessel disease underwent 3D MR imaging (1.5 T).
  • Gadolinium chelates were administered intravenously at 0.2 mmol/kg during MR acquisition.

Main Results:

  • Continuous infusion yielded significant preferential arterial enhancement (P < 10(-5)) without venous or background interference.
  • Correlation with angiography/surgery in 48 patients showed 88% sensitivity and 97% specificity for stenosis/occlusion.

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  • 100% sensitivity and specificity were achieved for detecting aortic or iliac artery aneurysms.

    • Conclusions:

    • Intravenous infusion of paramagnetic contrast material facilitates preferential arterial enhancement in MR aortography.
    • This method demonstrates high accuracy in diagnosing various aortic pathologies.