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Related Experiment Videos

[The recurrent multifocal pleomorphic adenoma]

M G Vigili1, F Sciarretta, A Marzetti

  • 1Divisione di Otorinolaringoiatria e Chirurgia Cervico-Facciale, Istituto per lo studio e la cura dei Tumori Regina Elena, Roma.

Acta Otorhinolaryngologica Italica : Organo Ufficiale Della Societa Italiana Di Otorinolaringologia E Chirurgia Cervico-Facciale
|January 1, 1993
PubMed
Summary
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Pleomorphic adenoma, the most common salivary gland tumor, frequently recurs after surgery. Inadequate surgical techniques like enucleation increase recurrence risk, necessitating better surgical approaches for pleomorphic adenoma management.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Head and Neck Surgery

Context:

  • Pleomorphic adenoma (P.A.) is the most common salivary gland tumor.
  • P.A. exhibits high recurrence rates (up to 50%) and a potential for malignancy (2-9%).
  • Recurrent P.A. can present with distant metastases and multiple nodules, even in the neck soft tissue.

Purpose:

  • To discuss six cases of recurrent pleomorphic adenoma with multiple recurrences after primary surgery.
  • To analyze the clinicopathological behavior and recurrence patterns of pleomorphic adenoma.
  • To evaluate surgical techniques and management strategies for primary and recurrent P.A.

Summary:

  • Six cases of pleomorphic adenoma with multiple recurrences, some presenting in the neck, were studied.

Related Experiment Videos

  • Inadequate surgical techniques, such as enucleation, are identified as a major cause of high P.A. recurrence rates.
  • Recommended surgical techniques for primary P.A. include lateral lobectomy or total conservative parotidectomy, with specific considerations for recurrent cases involving the facial nerve.

    • Impact:

    • Highlights the inadequacy of enucleation for pleomorphic adenoma excision, emphasizing the risk of tumor seeding.
    • Recommends appropriate surgical techniques (lateral lobectomy, conservative parotidectomy) to minimize recurrence.
    • Suggests nerve preservation and post-operative radiation as alternatives to nerve sacrifice in managing recurrent P.A. with facial nerve involvement.