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Related Experiment Videos

Maternal fever during labor--what does it mean?

C A Churgay1, M A Smith, B Blok

  • 1Department of Family Practice, University of Michigan Medical School, Ann Arbor 48118.

The Journal of the American Board of Family Practice
|January 1, 1994
PubMed
Summary

Maternal fever during labor alone does not significantly increase neonatal sepsis risk. However, using clinical criteria for chorioamnionitis can improve sepsis diagnosis and reduce unnecessary antibiotic use in newborns.

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Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Infectious Disease

Background:

  • Maternal fever is linked to chorioamnionitis and neonatal sepsis when accompanied by other clinical signs.
  • The risk of neonatal sepsis with isolated maternal fever during labor is less understood.

Purpose of the Study:

  • To investigate the association between isolated maternal fever during labor and the risk of neonatal sepsis.
  • To evaluate the utility of clinical chorioamnionitis criteria in managing neonatal sepsis risk.

Main Methods:

  • Retrospective review of 82 cases of maternal fever during active labor.
  • Analysis of clinical factors, chorioamnionitis criteria, and neonatal sepsis diagnoses.

Main Results:

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  • Of 46 women meeting chorioamnionitis criteria, 6 neonates had sepsis.
  • No significant differences in admission or intrapartum factors were found between women with or without chorioamnionitis.
  • Proposed criteria (chorioamnionitis + neonatal band cell/neutrophil ratio ≥ 0.2) improved positive predictive value and specificity for neonatal sepsis diagnosis, reducing antibiotic use by 17%.

    • Conclusions:

    • Maternal clinical criteria for chorioamnionitis can aid in selective intrapartum antibiotic administration.
    • These criteria can improve the prediction of neonatal sepsis risk.
    • Integrating these criteria may optimize newborn antibiotic management.