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Misleading hepatitis C serology following administration of intravenous immunoglobulin
R R Nixon1, S A Smith, R L Johnson
1Department of Pathology, Oregon Health Sciences University, Portland 97201-3042.
American Journal of Clinical Pathology
|March 1, 1994
Abstract:
Intravenous immunoglobulin (IVIG) is a blood derivative that is being evaluated for the prevention and treatment of numerous disorders. Recent studies have suggested beneficial effects from the prophylactic administration of IVIG to very-low-birth-weight neonates. A disadvantage of such therapy is misleading infectious disease serologic assays following administration of IVIG. The authors report a recent case in their neonatal intensive care unit of a 24-week gestational age girl with a misleading positive hepatitis C serology reaction following IVIG administration.