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Published on: January 7, 2019
Nosocomial blood-borne infection secondary to intravascular devices
D E Fry1, R V Fry, A P Borzotta
1Department of Surgery, Case Western Reserve University, Cleveland, Ohio.
Abstract:
A total of 143 patients with 159 episodes of intravascular device, blood-borne infection were studied. All infections were confirmed by the same organism being recovered from blood culture and by semiquantitative culture of the catheter tip. Sites of infection included the peripheral venous line (n = 72), central catheter (n = 49), arterial line (n = 18), subclavian dialysis catheter (n = 12), Swan-Ganz catheter (n = 4), Broviac catheter (n = 3), and transvenous pacemaker wires (n = 1). Staphylococcus aureus (n = 78) and Staphylococcus epidermidis (n = 33) predominated as pathogens. Excessive length of catheterization was implicated as directly responsible for this complication in patients with peripheral intravenous and arterial lines. Nosocomial staphylococcal bacteremia must be considered secondary to an indwelling intravascular device until proven otherwise. Appropriate therapy requires removal of the catheters, excision of the vein if suppuration or persistent bacteremia is identified, and specific antibiotic therapy.
Insights
Intravascular device infections are often caused by Staphylococcus aureus and Staphylococcus epidermidis. Prompt catheter removal and antibiotic treatment are crucial for managing these serious blood-borne infections.
Area of Science:
- Infectious Diseases
- Medical Microbiology
- Clinical Medicine
Background:
- Intravascular devices are essential for patient care but pose a risk for blood-borne infections.
- Nosocomial infections associated with intravascular devices are a significant clinical concern.
Purpose of the Study:
- To investigate the incidence, causative organisms, and management of intravascular device-related infections.
- To identify risk factors contributing to these infections.
Main Methods:
- Retrospective analysis of 159 episodes of intravascular device-related infections in 143 patients.
- Infections confirmed by matching blood cultures and catheter tip cultures.
- Identification of predominant pathogens and infection sites.
Main Results:
- Staphylococcus aureus (n=78) and Staphylococcus epidermidis (n=33) were the most common pathogens.
- Peripheral venous lines (n=72) and central catheters (n=49) were the most frequent sites.
- Excessive catheter dwell time was linked to infections in peripheral intravenous and arterial lines.
Conclusions:
- Nosocomial staphylococcal bacteremia should be presumed secondary to intravascular devices.
- Effective management includes catheter removal, potential vein excision, and targeted antibiotic therapy.
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