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Towards an understanding of structure-function relationships of elongation factor Tu
O Wiborg1, C Andersen, C R Knudsen
1Department of Biostructural Chemistry, Aarhus University, Denmark.
Biotechnology and Applied Biochemistry
|February 1, 1994
Abstract:
In light of the recently determined structure of elongation factor Tu, and taking into account chemical studies mapping functional sites, a number of residues have been selected for site-directed mutagenesis studies. Gly94, Gly126, His66, His118, Lys89 and Asp90 have each been point-mutated. Preliminary in vitro characterization data are presented.