Neurochemical bases for narcotic tolerance and dependence

7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors.

Journal of medicinal chemistry·1997

Spinal delta opioid receptor subtype activity of 6-monoacetylmorphine in Swiss Webster mice.

Pharmacology, biochemistry, and behavior·1997

Aspartic acid conjugates of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1(3-aminophenyl)-2-(1-pyrrolidi nyl) ethyl]acetamide: kappa opioid receptor agonists with limited access to the central nervous system.

Journal of medicinal chemistry·1996

Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors.

Journal of medicinal chemistry·1996

Arylacetamide-derived fluorescent probes: synthesis, biological evaluation, and direct fluorescent labeling of kappa opioid receptors in mouse microglial cells.

Journal of medicinal chemistry·1996

Cold water swim stress- and delta-2 opioid-induced analgesia are modulated by spinal gamma-aminobutyric acidA receptors.

The Journal of pharmacology and experimental therapeutics·1995

Gut microbiome crosstalk in acute myeloid leukemia: mechanisms, treatment-associated dysbiosis, and translational opportunities.

Biochemical pharmacology·2026

NQO1 at the crossroads of oxidative stress, cancer, and therapeutic innovation.

Biochemical pharmacology·2026

Targeting the β2-adrenergic receptor suppresses melanoma progression by disrupting the PKA-SOX10-MAGEA1 oncogenic axis.

Biochemical pharmacology·2026

Pharmacokinetic modeling frameworks for complex antibody-drug conjugates analytes: clinical pharmacology considerations.

Biochemical pharmacology·2026

Upadacitinib effectively suppresses IL13RA2 expression in primary human intestinal fibroblasts derived from Crohn's disease tissue.

Biochemical pharmacology·2026

Cordycepin protects against simulated microgravity-induced osteogenic impairment involving ferroptosis-related signaling.

Biochemical pharmacology·2026

High-frequency taVNS modulates olfaction-related brain activity in patients with subjective cognitive decline.

Frontiers in human neuroscience·2026

Ventral Column Spinal Cord Stimulation for Pain Management: Mechanisms, Clinical Evidence, and Future Directions.

American journal of physical medicine & rehabilitation·2026

Neuromodulatory roles of the sigma-1 receptor in behavior and drug sensitization during development.

Acta pharmacologica Sinica·2026

Implementation of bedside and intraoperative neurophysiological monitoring in the diagnosis of functional neurological symptom disorder following spinal surgery: illustrative case.

Journal of neurosurgery. Case lessons·2026

Serum Levels of Prestin, Otoferlin, Connexin 26, and Stereocilin: A Biomarker Approach to Tinnitus.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026

Effects of AC-SDKP administration on the NLRP3 inflammasome complex and blood-spinal cord barrier in experimental spinal cord injury.

Ultrastructural pathology·2026

Related Experiment Videos

Neurochemical bases for narcotic tolerance and dependence

Related Concept Videos

7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors.

Spinal delta opioid receptor subtype activity of 6-monoacetylmorphine in Swiss Webster mice.

Aspartic acid conjugates of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1(3-aminophenyl)-2-(1-pyrrolidi nyl) ethyl]acetamide: kappa opioid receptor agonists with limited access to the central nervous system.

Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors.

Arylacetamide-derived fluorescent probes: synthesis, biological evaluation, and direct fluorescent labeling of kappa opioid receptors in mouse microglial cells.

Cold water swim stress- and delta-2 opioid-induced analgesia are modulated by spinal gamma-aminobutyric acidA receptors.

Gut microbiome crosstalk in acute myeloid leukemia: mechanisms, treatment-associated dysbiosis, and translational opportunities.

NQO1 at the crossroads of oxidative stress, cancer, and therapeutic innovation.

Targeting the β2-adrenergic receptor suppresses melanoma progression by disrupting the PKA-SOX10-MAGEA1 oncogenic axis.

Pharmacokinetic modeling frameworks for complex antibody-drug conjugates analytes: clinical pharmacology considerations.

Upadacitinib effectively suppresses IL13RA2 expression in primary human intestinal fibroblasts derived from Crohn's disease tissue.

Cordycepin protects against simulated microgravity-induced osteogenic impairment involving ferroptosis-related signaling.

High-frequency taVNS modulates olfaction-related brain activity in patients with subjective cognitive decline.

Ventral Column Spinal Cord Stimulation for Pain Management: Mechanisms, Clinical Evidence, and Future Directions.

Neuromodulatory roles of the sigma-1 receptor in behavior and drug sensitization during development.

Implementation of bedside and intraoperative neurophysiological monitoring in the diagnosis of functional neurological symptom disorder following spinal surgery: illustrative case.

Serum Levels of Prestin, Otoferlin, Connexin 26, and Stereocilin: A Biomarker Approach to Tinnitus.

Effects of AC-SDKP administration on the NLRP3 inflammasome complex and blood-spinal cord barrier in experimental spinal cord injury.

Related Experiment Videos

Neurochemical bases for narcotic tolerance and dependence

Related Concept Videos

Related Articles